[2] She studied at the Dagtekenschool voor meisjes [nl] (English:Day drawing school for girls) in Amsterdam.
She also received instruction from Henriëtte Asscher, Meijer de Haan, Wilhelmina Cornelia Kerlen, Bartol Wilhelm van Laar, and Jan Zürcher.
[3] In 1891 she married fellow artist Karel Alexander August Jan Boom (1862-1943).
[3] Pothuis' work was included in the 1939 exhibition and sale Onze Kunst van Heden (Our Art of Today) at the Rijksmuseum in Amsterdam.
[5] In June 1896 she opened a photography studio with her colleague Anna Sluijter.