Lady Charlotte was the first of twenty-one 'ladies of quality and distinction'[1][2] who signed Thomas Coram's first petition, presented to King George II in 1735, calling for the establishment of the Foundling Hospital.

He was known as "The Proud Duke",[3] and is said to have reproached her, after she had gently tapped him on the shoulder with her fan, with the words: "Madam, my first wife was a Percy and she never took such a liberty".

[5] However, correspondence between one of her descendants and the curator of the Foundling Museum's 2018 exhibition, "Ladies of Quality & Distinction",[6] cites the family bible, which gives her year of birth as 1693.

In Eliza Haywood's 1726 satire, The Secret History of the Present Intrigues of the Court of Carimania, the duchess is referred to under the pseudonym of "Euridice", while the duke was "Doraspe".

[5] In his efforts to establish the first Foundling Hospital, Thomas Coram approached ladies of nobility to support his petition to King George II.