Charni Road (Marathi pronunciation: [t͡ʃəɾniː ɾoːɖ]) is a neighbourhood in the southern part of Mumbai.

Many people originally from Chendni migrated to South Mumbai to the area which is known today as Charni Road.

In 1884, Sir Adamji Peerbhoy (1845–1913), a well-known philanthropist from Mumbai, India, built several properties (a Bohra kabrastan (cemetery/burial ground), Masjid, Sanatorium, and Amanbai Charitable Hospital later known as Saifee Hospital on Charni Road opposite the railway station.

He wanted to provide a safe haven for the travellers, poor, or needy to rest, use the masjid for prayers, or the hospital if they needed it.

After Sir Adamjee Peerbhoy's death, his grandson Akbar, against the wishes of the family, converted the properties into a trust.