He played college football for the Fordham Rams and was selected by the Arizona Cardinals in the fourth round of the 2018 NFL draft.

Edmonds grew up in Harrisburg, Pennsylvania and graduated from Central Dauphin East High School, where he played basketball and football for the Panthers.

He was selected to play in the Big 33 Football Classic and was named the game's Most Valuable Player.

[1] Despite his success on the field, he garnered little interest from Football Bowl Subdivision programs due to his size.

In his final season with the Rams, Edmonds was injured and only played in seven games, rushing for 577 yards on 136 attempts with five touchdowns.

[11] During Week 7 of the 2019 season against the New York Giants, Edmonds posted his first career 100+-yard game as he finished with 126 rushing yards with three touchdowns, helping the Cardinals win 27–21.

[13] In Week 7 of the 2020 season against the Seattle Seahawks, Edmonds recorded 145 yards from scrimmage during the 37–34 overtime win.

[15] Edmonds entered the 2021 season as the Cardinals starting running back for the first time of his career, ahead of free agent signee James Conner.