He made his acting debut in 2022 in the TV series Cutie Pie, achieving fame and being nicknamed "Son of the nation"[1][2] and "Pearl of Asia".

[6][10] He debuted in 2022 in Cutie Pie, playing Kuea Keerati opposite Pruk Panich:[12] the success of the BL romance series shot him to stardom overnight, both in Thailand and abroad,[13] and Howe Magazine included him in the list of the 50 most influential people of the year.

[22] On September 30 and October 1, 2023, Perdpiriyawong and Pruk Panich held a sold-out joint concert at Thunder Dome, Muang Thong Thani: both shows were followed by 4,000 people onsite and over 15,000 online.

[25] In 2024, he released several singles, including international collaborations like "Blooming Just For You" with South Korean singer Paul Kim[26] and the theme song for Nippon Haku Bangkok festival, "Dream 2024 (Paint the Future)", with Kokoro Kohatsu from the Japanese band Psychic Fever from Exile Tribe.

[27] On August 10 and 11, he held his first concert titled Dream Catcher at the Impact Arena, Muang Thong Thani, selling out more than 20,000 tickets for both days.