[2] Keller was born in Jerusalem to Menachem Mendel and Shulamit Lubin.

[3] She completed her master's and doctoral degrees at the Einstein Institute of Mathematics in the Hebrew University of Jerusalem,[4] under the supervision of Professor Micha Asher Perles.

Among her contributions to the field, together with other researchers, are the solution of Ringel's problem on coloring tangency graphs of circles in the plane,[5][6] improved algorithms for finding conflict-free colorings of geometric hypergraphs, which has applications to frequency allocation for cellular antennas,[7] and finding effective quantitative bounds for the (p,q) theorem[8][9] in convexity theory.

Keller won the Baroness Ariane de Rothschild Fellowship for Outstanding Female Doctoral Students (in the first cohort of recipients), the Hoffman Fellowship for Outstanding Doctoral Students, and the Noriko Sakurai Award for an Outstanding Postdoctoral Fellow at the Center for Advanced Studies in Mathematics at Ben-Gurion University.

In 2022, she was selected for TheMarker's 40 Under 40 list, and in 2024 she won the Krill Prize awarded by the Wolf Foundation.