[4] Kane made her professional acting debut in the 2001 short film entitled Failure of Pamela Salt.

She went on to guest star in the television series Cracking Up, Listen Up, the pilot episode of Summerland and the 2004 direct-to-video film Arizona Summer.

From 2010 to 2014, Kane co-starred in the Disney Channel animated series Fish Hooks voicing the role of Bea Goldfishberg.

In 2010, Kane filmed a web series called "The Homes" written and directed by John Cabrera.

[6] In 2011, Kane joined the cast of the final season of The CW's One Tree Hill in a recurring role.