She voiced Kate Cha / Dupli-Kate in the Amazon Prime Video animated series Invincible.

When Unfabulous ended in 2007, Jow co-starred in the film Bratz: The Movie as Quinn and has guest-starred on the shows Wizards of Waverly Place, The Young and the Restless, iCarly, The Secret Life of the American Teenager and the Disney Channel series Hannah Montana and co-starred in the 2009 science fiction comedy Aliens in the Attic.

[6] In 2011, Jow began a recurring role in the second season of the Nickelodeon musical sitcom Big Time Rush as Lucy Stone, an aspiring rock musician and a brief love interest of Kendall Knight (Kendall Schmidt) and later on becomes the love interest of James Diamond (James Maslow).

[7] In 2012, Jow starred in The CW drama pilot Shelter, produced by J. J. Abrams and Mark Schwahn, where she played Morgan.

[9] That same month, it was also announced that Jow would reprise her role as Lucy Stone on Big Time Rush in the fourth and final season.

[11] Later that month, it was announced that Jow would be joining the CW science fiction romantic drama pilot Oxygen, as Julia Yeung, a girl who has an illness which may be cured by aliens.

[16] On August 25, 2015, Malese was announced to be reprising her role as Linda Park as a friend of Iris for multiple episodes.