ChemSec argued in favour of tighter controls on chemicals in Europe under REACH, publishing analyses which contradicted industry estimates of the economic impact of the legislation.

In 2010 ChemSec was commissioned to produce a research report on flow of information in the electronics supply chain for the International Conference on Chemicals Management (ICCM) programme within the United Nations Environment Program.

ChemSec argued in favour of stricter controls on chemical use on the basis of commercial advantages[4] and scientific evidence of benefits to human and environmental health.

[8] In 2010, ChemSec secured support from some manufacturers for their proposals[9] to restrict the use of brominated flame retardants and PVC in electronic goods under the RoHS Directive.

[12] The move, via ChemSec's SIN List initiative, coincides with EU plans over 2011–2012 to develop accepted regulatory criteria for endocrine disruptors (EDCs) and further restrict their use.

In 2011 the group had the following members:[19] ChemSec has published reports presenting arguments from companies in favour of stricter chemicals regulation under REACH[20] and tougher restrictions on halogenated compounds under the RoHS Directive, as described in a number of business position statements.