After defeating Pai Yu-po, the lower ranked Chinese Taipei's player in the first round, she set her meeting with the top seeded Akane Yamaguchi.

[20] This was not over yet, in the quarter-final, she defeated another higher seeded player, the former world champion Ratchanok Intanon in 3 games & assured herself of first ever medal in this elite event.

In the group stage, she lost to Tai Tzu-ying (1–2) but won against Sung Ji-hyun (2–0) & Ratchanok Intanon (2–1) which meant she could confirm her place in the semifinal.

[24] In the World Championships, she failed to cross the quarter-final after being downed by Akane Yamaguchi, a player Chen defeated last year in straight games.

[28] She again qualified for taking part in the season-ending championships, this time renamed as the "World Tour Finals", which was held in her home country China.

In the final group match, she twisted her ankle in the very early stage of 1st game which forced her to retire and her overall campaign ended.

[29] 2019 proved the best ever year in Chen Yufei's career as she earned multiple titles and honour of becoming the most dominant player of 2019 in her category.

[32] In the 2019 Sudirman Cup, she helped her team to win the record-breaking 11th title, in which she scored a point by defeating Akane Yamaguchi, and eventually Japan was crushed in the final with 3–0 tally by China.

[33] Her best form wasn't dipped yet, as she claimed the next title in the Australian Open by totally outplaying Nozomi Okuhara in the final with a very one-sided scoreline 21–15, 21–3.

[35] With all her success in 1st half of the year, she was considered as China's best contender for gold in 2019 BWF World Championships in her category.

In the quarter-final, she was tested severely by Danish Mia Blichfeldt who once appeared to create an upset by leading 15–12 against her in the decider, but Chen's persistence led her way to the victory and assured her of second medal in this Grade 1 event.

She won the 2019 Fuzhou China Open again, by beating the same opponent from the last year, Nozomi Okuhara, but this time with tougher opposition.

[37] After beating Ratchanok Intanon in the final, she won her 6th World tour title by winning the Hong Kong open.

[38] Going into the 2019 BWF World Tour Finals as the best title winning contender, in the group stage, she downed all her opponents P. V. Sindhu (2–1), Akane Yamaguchi (2–0) and He Bingjiao (2–0) to reach the semifinal.

[39] In the final, she showed a great fighting spirit to beat Tai Tzu-ying after being a game down and won the title 12–21, 21–12, 21–17.

[47] She helped the national team defend the Sudirman Cup title at home soil after delivering the final win against An Se-young in straight games.