[4] From 4th to 7th Streets is it discontinuous because of the U.S. Mint, Independence Mall, and the Federal Reserve Bank of Philadelphia.

A half-block of it, from Broad to Carlisle Streets, has been converted into a plaza and sculpture garden for the Pennsylvania Academy of the Fine Arts.

It is continuous from Carlisle to 23rd Street (the Schuylkill River), except for a slight jog at the Benjamin Franklin Parkway.

[5] Among the residents was former-slave James Oronoko "Noke" Dexter, one of the founders of the African Episcopal Church of St. Thomas.

Archaeologists excavated the site of Dexter's house in 2003, prior to the building of the National Constitution Center.