Chiang Khan (Thai: เชียงคาน, pronounced [t͡ɕʰīa̯ŋ kʰāːn]) is a district (amphoe) in the northern part of Loei province, northeastern Thailand.

The important water resources are the Mekong, Hueang, and Loei Rivers.

Chiang Khan became a trading hub largely due to its location on the river.

[1] Chiang Khan was used as the main setting for the 2014 romantic comedy Chiang Khan Love Story (Tookae Ruk Pang Mak), directed by Yuthlert Sippapak.

[2] Chiang Khan was referenced in 2018–19 TV drama's Channel 7 HD Nai Keun Nao Sang Dao Yung Oun as a backdrop for the story.