Chicago, Rock Island and Pacific Railroad-Wilton Depot is an historic building located in Wilton, Iowa, United States.

The Mississippi and Missouri Railroad built the first rail line in 1855 in what would be called Wilton Junction.

A wooden frame depot and a separate freight facility served the community.

The railroad placed their repair and maintenance center in Wilton, and it remained here until 1881 when they started to move operations to Davenport and Muscatine.

After the building served as a freight depot it went into decline until the Wilton Historical Society obtained and restored it.