The Cabinet Chief is not a prime minister, as in Argentina's presidential democracy the role of head of government is still bestowed upon the president.

[3] It was part of the agreements brokered by the two largest parties in Argentina at the time, the Justicialist Party (PJ) and the Radical Civic Union (UCR), in what is now known as the Pact of Olivos; the UCR, then led by former president Raúl Alfonsin, sought to reduce the significant political powers of the Presidency and shift towards a parliamentary system.

[4][7] In the end, however, the overarching nature of Argentina's political system following the reform remained decidedly presidential, as the Chief of the Cabinet of Ministers acts more as an extension of the President to whom the head of state may delegate a certain number of responsibilities, while also being constitutionally obligated to report to the National Congress.

Specifically, articles 100 and 101 state: Second Part: Authorities of the Nation Chapter IV The Chief of the Ministerial Cabinet and other Ministers of the Executive Power Section 100.- The Chief of the Ministerial Cabinet and the other secretary ministers, whose number and powers shall be determined by a special law, shall be in charge of the business of the Nation and shall countersign and legalize the acts of the President with their signatures, without which said acts are void.

10.- Once the ordinary legislative session of Congress has begun, to submit together with the other ministers a detailed report on the state of the Nation regarding the business of the respective departments.

The second seat is the Secretariat of Management and Public Employment Building (former "Banco Argentino-Uruguayo"), located on Diagonal Norte and San Martín streets in Buenos Aires.

The building was designed by French architect Eduardo Le Monnier, and was seat of defunct Ministry of Modernization,[13] created during the administration of Mauricio Macri in 2015.