Chimaphila maculata (spotted wintergreen, also called striped wintergreen, striped prince's pine, spotted pipsissewa, ratsbane, or rheumatism root) is a small, perennial, evergreen herb native to eastern North America and Central America, from southern Quebec west to Illinois, and south to Florida and Panama.

The variegation of the leaves arises from the distinct white veins contrasted with the dark green of the leaf.

The flowers mature to small (6–8 mm (0.24–0.31 in) in diameter) capsules bearing the seeds of the plant, which are dispersed by the wind.

"The Creek Indians called it 'pipsisikweu' – which means 'breaks into small pieces' – after the supposed ability to break down gallstones and kidney stones.

Native Americans used its leaf tea to treat rheumatism and stomach problems, and crushed leaves were applied as a poultice to sores and wounds.