The first generation DF8 is powered by the original 3,310 kW (4,440 hp) 16V280ZJ engine, manufactured by Qishuyan Locomotive and Rolling Stock Works.

The second generation, DF8B, is powered by an updated 16V280ZJA engine with 3,680 kW (4,930 hp), whose production started in 1997.

Now it is owned by Liuzhou Locomotive Depot, Nanning Railway Bureau.

The DF8BJ, which uses the 16V280ZJG engine (4,000 kW or 5,400 hp), GTO VVVF inverter and AC traction motors, was produced by Ziyang.

It was equipped with a 16V280ZJB (R16V280ZJ) engine (maximum power 4.4 MW or 5,900 hp) and AC traction motors.

Ziyang made a special DF8B which was originally intended to be used on the Qingzang line and was numbered DF8DJ-0001.

It's now running on Xiyan Line in Shaanxi and has been remodified with dual-fuel engine (LNG & diesel oil).