Written by Walter Ferreira Ramos and Delia Maunas, and produced by Cris Morena and RGB Entertainment, the series has been aired on Disney Channel in some South American countries, Mexico,[1] Greece and Spain.

Magali Garcia (Jorgelina Aruzzi) is a strict businesswoman who got pregnant in the past, and after revealing it to her father Vítor (Ernesto Claudio), was sent to an abandoned place.

Magali started looking for the baby, and when she is sure it lives in the Modelo Dumont orphanage, she goes there under a new identity: the sweet, adorable, funny, offbeat Lili, helped by her best friend Lúcia (Mariana Richaudeau).

Lili also meets Terezinha (Mariana Briski), an arrogant housekeeper the kids see as an "evil witch"; the orphanage's owners Julieta (María Carámbula) and Pierre (Alejo García Pintos) Dumont; and their spoiled children Marcel (Luciano Ruiz) and Talita (Delfina Varni).

The chiquititas of this series are Miki, Guta, and Mosquito, teenagers forming a loving triangle; the younger orphans are Luana, Anita, Nando, Paula, Pulga, Josep, Eduardo, and Francisco.