Chissey-en-Morvan (French pronunciation: [ʃisɛ ɑ̃ mɔʁvɑ̃]; lit.

"Chissey-in-Morvan"), commonly referred to simply as Chissey, is a rural commune in the Saône-et-Loire department in the Bourgogne-Franche-Comté region in central-east France.

Bordering both Nièvre and Côte-d'Or, it is part of Morvan Regional Natural Park.

The Buis hoard of 7th-century gold coins was found in Chissey-en-Morvan in 1855.

On 26 June 1944, amid World War II, German occupying forces motivelessly executed three local teenagers in Vauchezeuil, northeast of the village of Chissey-en-Morvan, who happened to be passing through.