Chistochina (Tsiis Tl’edze’ Caegge[2] in Ahtna Athabascan) is a census-designated place (CDP) in Copper River Census Area, Alaska, United States.

Chistochina began as an Ahtna Athabascan fish camp and a stopover place for traders and trappers.

The village access road later became part of the Valdez-Eagle Trail, constructed by miners during the gold rush to the Eagle area in 1897.

The area was settled by homesteaders, although it has remained the most traditional of all Ahtna Athabascan villages.

Chistochina is the most traditional Ahtna village and is home to the Cheesh Na' Tribe.