Chloe Aurelia Clark Willson (April 16, 1818 – June 2, 1874) was an early pioneer of what became the U.S. state of Oregon, and one of the first teachers of the Methodist mission in the Willamette Valley.
[2] At the age of 21, she sailed from New York on the ship Lausanne in what was known as Jason Lee's "Great Reinforcement" of recruits for the Methodist Mission in Salem, Oregon.
[2] Chloe Willson was the first teacher of the Oregon Institute, which was founded after the failure of the Indian Manual Training School.
When the Donation Land Claim Law of 1850 passed, it meant the 640 acres (260 ha) held by Willson belonged jointly to him and Chloe.
He was bound to the Oregon Institute's board to administer the land, but Chloe was not, leading to controversy which was settled in 1854 with a compromise: the property was split in half along State Street, with the 320 acres (130 ha) South of the street belonging to the institute (later Willamette University), and the 320 acres (130 ha) North belonging to Chloe.