He was founder and CTO of Internet Security Systems (ISS), a company which he started in the early 1990s, and then sold to IBM in 2006 for $1.3B.

He also holds the honor of being the namesake of the Klaus Advanced Computing Building at the Georgia Institute of Technology.

Klaus formed ISS in the early 1990s as a student at the Georgia Institute of Technology, eventually dropping out to focus on the growing company.

[2][3][4] In July 2014, Klaus co-founded NeuroLaunch, a business accelerator focused towards neurotech companies in Atlanta.

[9] However, he was unable to attend due to the passing of his son, Will,[10] and had his friend Karl Dasher give the address instead.