He worked in Copenhagen and was the doctor responsible for Christine Jorgensen's sex reassignment, and she would choose her name in honor of him.
[5] Hamburger received international attention in 1952[4] after treating Christine Jorgensen, an American transgender woman who wanted a male-to-female sex reassignment.
Hamburger felt that it was unethical to deny medical treatment to transgender women in order to make their lives "as tolerable as possible".
Gordene Olga MacKenzie, the author of the 1994 book Transgender Nation, referred to Hamburger and Harry Benjamin as "the two pioneering figures most responsible for the creation of modern clinical transsexual ideology".
[2] Richard F. Docter, who authored a 2013 biography of Jorgensen, wrote of Hamburger: "He is seldom credited with being the inventor of the modern protocol for transsexualism, but he was.