His paternal grandfather was the English actor and comedian Leslie Henson, who was perhaps best known for founding the Entertainments National Service Association (ENSA) during the Second World War.
After attending Holland Park Comprehensive in the 1980s,[8] Henson worked for three years as a baker, with a home studio that he used in his spare time.
[10][11] Henson gained a 2007 Ivor Novello Awards nomination for 'Best Original Movie Score' for his work on the 2006 film Severance.
The company is a producer of musical "virtual instruments", and has collaborated with noted film composer Hans Zimmer, as well as Chad Smith of the Red Hot Chili Peppers, Olafur Arnalds, Roger Taylor of Queen, Eric Whitacre, and most recently with the BBC Symphony Orchestra.
On 24 February 2023, Henson announced that he would be stepping away from Spitfire Audio following backlash to a tweet supporting Graham Linehan and J. K. Rowling.