Christian Jacob Theophilus de Meza (November 26, 1756 – April 6, 1844) was a Danish physician and author.

De Meza was born into a Jewish family Copenhagen in 1756.

He also wrote a drama, Dormon og Vilhelmine that was produced at the Royal Theatre, Copenhagen, in 1796.

His eldest son /by his first wife), Christian Julius de Meza (1792–1865), was a general in the Danish army during the Second Schleswig War.

His former property at the corner of Stengade and Sophie Brahes Gade is still known as the De Meza House after him in spite of the fact that the present corner building was built by a later owner.