The organisation campaigns for and promotes traditional Christian values within the British medical sector, and publishes two journals, Triple Helix (for doctors) and Nucleus (for students), several smaller publications, and some books.

CMF regularly contributes to debate on issues of medical ethics, such as making submissions to the UK House of Lords enquiry into physician-assisted suicide, and is opposed to legal access to abortion and euthanasia in the United Kingdom.

[1] The Christian Medical Fellowship has been the subject of complaints from several Hindu leaders to the House of Lords Select Committee on Religious Offences objecting to a claim that Hinduism was a "false religion".

[2] In October 2007, the Christian Medical Fellowship was accused by The Guardian newspaper of attempting to skew the balance of evidence presented at the Parliamentary review of the UK's laws on abortion due to a number of its members presenting evidence at the Parliamentary Select Committee without revealing their membership and seniority within the organisation.

The members concerned stated that they were submitting evidence as individuals, not as representatives of CMF, and they declared their affiliation when asked to do so in an unusual step by the Committee.