[1] Uphoff was a member of the Illinois State Redbirds for four seasons, redshirting his true first year.
[2] He was named honorable mention All-Missouri Valley Football Conference as a redshirt sophomore after breaking up seven passes with one interception.
[4][5] Uphoff signed with the Green Bay Packers as an undrafted free agent shortly after the conclusion of the 2021 NFL draft.
[7] On December 29, 2022, Uphoff signed with the BC Lions of the Canadian Football League (CFL).
[9] Uphoff is a member of the Church of Jesus Christ of Latter-day Saints and was baptized by his teammate Bronson Kaufusi on August 30, 2021.