He has also played in the NBA for the Philadelphia 76ers, Charlotte Hornets, Milwaukee Bucks, New Orleans Pelicans, Detroit Pistons, Houston Rockets and the Dallas Mavericks.

[3] In Findlay, he helped the Pilots win 54 consecutive games and an ESPN National High School Invitational championship in 2012.

[22] On November 7, he made his debut for the Hornets in a 122–100 win over the Indiana Pacers, recording two rebounds in three minutes off the bench.

[25] Wood would later join the Dallas Mavericks and Phoenix Suns for the 2017 NBA Summer League out in Orlando and Las Vegas, respectively.

[26][27] Wood was a member of the Mavericks team that won the Summer League Championship in Orlando that year.

[34] On March 26, he put up 23 points, nine rebounds, six blocks, three steals and an assist in over 32 minutes in the Pelicans' loss to the Hawks.

[38][39] On November 24, 2020, Wood was signed to a three-year, $41-million contract by the Pistons and traded to the Houston Rockets in exchange for Trevor Ariza, the draft rights to Isaiah Stewart, a future second-round pick, and cash considerations.

[40] On December 26, 2020, Wood made his Rockets debut, putting up 31 points, 13 rebounds, three assists, and one block in a 128–126 overtime loss to the Portland Trail Blazers.

[41] During a road trip game win against the Memphis Grizzlies, Wood suffered a right ankle injury and left the arena in the third quarter.

[46] On June 24, 2022, Wood was traded to the Dallas Mavericks in exchange for Boban Marjanović, Trey Burke, Marquese Chriss, Sterling Brown, and the draft rights to Wendell Moore Jr.[47] Wood became the first player in franchise history to score at least 25 points each in his first two games.

[48] On December 25, 2022, in his first Christmas Day game, Wood recorded 30 points, 8 rebounds, 7 assists, 4 steals and 2 blocks in a 124–115 victory over the Los Angeles Lakers.

After exercising his $3 million player option to return for another season, Wood had arthroscopic surgery on his knee again in September.