He originally chose to play college basketball with the LIU Brooklyn Blackbirds, but switched to Baylor due to a coaching change within the former program.

[3] Entering his fourth season, Fran Fraschilla labeled him as a strong candidate for Big 12 Player of the Year in 2015–16.

[21] He made his Nets debut two days later, recording 15 points, eleven rebounds, two assists and two steals in a 127–126 overtime loss to the Minnesota Timberwolves.

[22] On November 1, Prince scored a season-high 27 points, alongside twelve rebounds, in a 123–116 win over the Houston Rockets.

After the game on November 12, 2019, against the Utah Jazz, Prince traded jerseys with former Baylor Bears teammate Royce O'Neale.

[24] On January 14, 2021, Prince and center Jarrett Allen were traded to the Cleveland Cavaliers in a multi-player, four-team deal with the Houston Rockets and Indiana Pacers that sent James Harden to Brooklyn.

[25] Prince made his Cavaliers debut on January 20, recording 17 points, seven rebounds and four assists in a 147–135 double-overtime win over the Brooklyn Nets.

[28] On August 3, 2021, Prince, alongside a 2022 second-round pick and cash considerations, was traded to the Minnesota Timberwolves in exchange for Ricky Rubio.

[29] Prince made his Timberwolves debut on October 20, recording five points, three rebounds and two assists in a 124–106 win over the Houston Rockets.

[39][40] In the summer of 2015, following his junior season, Prince helped the United States men's national basketball team win the bronze medal at the 2015 Pan American Games.

[4] On August 25, 2022, Prince was arrested on a "fugitive warrant-out-of-state extradite" at Miami International Airport on account of a "dangerous drugs" charge from Texas.

[43] Prince honored his mother, Tamiyko, by wearing her maiden name, Waller, on the back of his jersey as Waller-Prince while playing for the Baylor Bears.