[1] In 1899, following expansion of the local area it served to include Ainsdale, the Infirmary merged with The Eye, Ear and Throat Hospital.

During the First World War, a further 120 beds for wounded soldiers where needed and saw the construction of yet another ward, a new Anaesthetic Room and Pathology Department in 1916.

After the First World War an Artificial Sunlight Department was added to the facilities as well as further accommodation for the staff and the construction of more wards and minor improvements to the hospital services as the town grew.

The Maternity services where independently managed, although the Infirmary provided the nursing, food, medicine, laundry and other requirements.

In 1943 the hospital services were becoming stretched due to the demand of health care, this was when the Appointments System for outpatients was introduced, this provided follow-up clinics for the 173 wounded soldiers which were admitted during the year.

Plans were put in place for the building of the Southport and Formby District General Hospital on the former Kew Gardens site on Town Lane.

[2] The Christiana Hartley maternity unit and the other remaining services provided on the infirmary site moved to new accommodation at the Southport and Formby District General Hospital in 1999.