Christine Guthrie

[1] Elected to the National Academy of Sciences in 1993,[2] Guthrie edited Guide to Yeast Genetics and Molecular Biology, an influential methods series for many years.

[7] She was the daughter of Brooklyn native and humorist Irene Kampen, whose book, Life Without George, was the basis for The Lucy Show, which aired for six seasons on CBS in the 1960s.

[4] After a tough pre-tenure review in 1976, she found support in a group of women and men who met informally for 20 years to help each other thrive in academia.

2 In work described in her citation for the Genetics Society of America Medal as a “macromolecular tour de force”, she cloned and sequenced the SNR genes for the yeast snRNAs.

[1] To accomplish this feat, she had to invent methods to discriminate functional snRNAs from degradation products and also to create widely used intron-containing reporter genes.