For her work, she has been recognized by Burkina Faso's Order of Merit and France's Legion of Honour.
As a volunteer for a local organization, she advocated for HIV testing and acted as a liaison between patients and physicians.
[2] In 2001, as part of her activism work, Kafando became the first Burkinese woman to publicly disclose her HIV-positive status.
[1][2][3] She is credited with encouraging then-president Blaise Compaoré to declare his support for HIV/AIDS-related efforts, and to publicly announce that he himself would be tested for HIV.
[1][2] Kafando founded and serves as president of Espoir Pour Demain (Hope for Tomorrow), which serves children with HIV/AIDS in Bobo-Dioulasso, raises awareness on mother-to-child transmission of HIV, and trains youth to become peer educators.