[4] She joined the diplomatic service in the Federal Department of Foreign Affairs in 1991, first as a stage in the International Law Section, then in 1992 as an attaché at the Swiss Embassy in Rabat, Morocco.

During this time, she dealt with the establishment of the human rights dialogue with the People's Republic of China, lectured and published on the UN Convention on the Elimination of All Forms of Discrimination Against Women (CEDAW) and attended the 1995 World Conference on Women in Beijing as a member of the Swiss delegation.

She was Secretary-General of the International Humanitarian Investigation Commission (IHEK), coordinator of the Counter-Terrorism Working Group in the FDFA, member of the Anti-Trafficking Coordination Unit (KSMM) of the Federal Department of Justice and Police (FDJP), co-chair of the Cluster on Clustering Convention 2008 in Dublin and President of the FDFA section of the Union of the Federal Association of Employees (PVB).

Schraner Burgener had her first ambassadorship from 2009 to 2015 as the Swiss ambassador to Thailand, succeeding Rodolphe Imhoof.

According to statements of the then German ambassador to Thailand Rolf Peter Gottfried Schulze, she is the only diplomat to have maintained contact with both camps during the 2013–2014 Thai political crisis.