She began her cycling career in 1996 as a mountain biker for Team Breezer run by Joe Breeze while still living in her hometown of Manhattan.

In 2008, she relocated to Mill Valley, California, to pursue her goal of becoming a professional which she achieved two years later.

In addition, she has made many appearances to the podium of UCI International events, including a few wins.

Vardaros has been profiled in many magazines, newspapers and other media outlets for her cycling accomplishments as well as for her vegan diet.

In addition, Vardaros is spokesperson for In Defense of Animals, The Vegan Society, and Physicians Committee for Responsible Medicine.