She was given a strict Protestant upbringing by her aunt Elizabeth, Dowager Duchess of Saxony.
Christine received a proposal from King Eric XIV of Sweden, but this did not come about.
As duchess, Christine supported churches and schools and scholarships to poor students in theology.
As a widow after 1586, Christine defended the rights of her son Philip against the council.
On 17 December 1564 Christine was married to Duke Adolf of Holstein-Gottorp and had the following children: Through her daughters Sophia and Anna, she is an ancestor of British Monarch Charles III.