Christoph Jacob Trew (16 April 1695 in Lauf an der Pegnitz – 18 July 1769) was a German physician and botanist.

He then travelled as part of the peregrinatio academica or grand tour around Europe for three years, making friends in Switzerland, Leiden, Danzig and Königsberg.

He was originally a city solicitor, court physician, Count Palatine of the Holy Roman Empire, an advisor to the Margrave of Brandenburg-Ansbach.

He was then elected to the local Collegium Medicum and supervised the Nuremberg's Theatrum Anatomicum as well as the Hortus Medicus, where plants of use in medicine where grown.

Along with other colleagues he founded a journal Commercium Litterarium, ad rei medicae et scientiae naturali incrementum (Learned Correspondence to the Advancement of Medicine and the Natural Sciences) in 1731.

erected the monotypic African genus Afrotrewia in the family Euphorbiaceae, named in Trew's honour.