Thereafter she made eight voyages as a slave ship in the triangular trade in enslaved people.

Captain John Howard sailed from Liverpool on 3 April 1785 for the Bight of Biafra and Gulf of Guinea islands.

Christopher departed Dominica on 4 January 1788 and arrived back at Liverpool on 16 February.

[1] Maxwell sailed from Liverpool on 8 June 1788 and arrived at Dominica on 29 December;[10] she had embarked 391 slaves and disembarked 246,[9] for a mortality rate of 18%.

Christopher sailed from Dominica on 10 January 1789 and arrived back at Liverpool on 11 February.

[11] On 14 May 1790 Captain Thomas Lowe sailed Christopher to West Central Africa and St. Helena.

Christopher sailed from Dominica on 28 January 1791 and arrived back at Liverpool on 7 March.

[12] Molyneux again sailed to West Central Africa and St. Helena, leaving Liverpool on 19 June 1791.

Supposedly, she embarked 273, of whom two men and two women died before she left the African coast.

Christopher sailed from Dominica on 11 January 1792 and arrived back at Liverpool on 31 February.

[18] On her way to Africa, Christopher was west of Madeira when she encountered a French privateer; an engagement ensued.

Captain Molyneux divested the privateer of her guns, small arms, shot, ammunition, and those of her stores (except provisions) that he needed, and then left her.

[17] Lloyd's List reported in February 1794 that Christopher, Molyneux, master, had sunk at St Croix.