He was a founder member of The Club, Samuel Johnson's dining circle.
On 25 June 1765 he was admitted a licentiate of the College of Physicians of London, and in the same year he was elected a Fellow of the Royal Society.
The book begins with an account of a successful treatment by him in June 1751 of a servant-maid who had been bitten by a mad turnspit dog in two places, and had rabies.
Later sections discuss the mental and physical aspects of the disease, its resemblances to hysteria, and some proposed remedies.
Edmund Burke was his patient around 1750; and married his daughter Jane Mary, brought up a Catholic, early in 1757.
[8] A Barbados estate, Boarded Hall, arising as a legacy from Sir Edmund Nagle who died in 1830, came partially under the control of John Nugent's eldest son Christopher Richard Nugent.
He sailed to Valparaiso in 1823, appointed by George Canning in 1823 the first consul-general to Chile, with Henry William Rouse and Matthew Carter.
After Margaret died, James Hill remarried to Elizabeth, daughter of Charles Dean Oliver.