During his training, he spent 18 months as a Research Registrar at University College Hospital to undertake an epidemiological study of schizophrenia in Inner London.
In 1992, he was awarded the Lilly Travelling Fellowship of the Royal College of Psychiatrists and the King Edward's Hospital Fund for London, England.
During this year, he was Travelling Research Fellow with the National Institute of Mental Health (Washington, DC), where he worked with Dr. Richard Coppola and Dr. Daniel Weinberger, developing a technique for volumetric analysis of brain MRI images.
After his return from England at the end of 1992, Prof. Christos Pantelis worked at the Mental Health Research Institute and at Royal Park Psychiatric Hospital.
He is currently Clinical Director and Principal Specialist for the Adult Mental Health Rehabilitation Unit (AMHRU) at Sunshine Hospital.
In particular they have demonstrated that brain structural abnormalities are occurring during the transition phase to psychosis in individuals at high risk for developing schizophrenia.