[3] In 1986, he began working for Eclipse Comics, writing Airboy which was edited by Timothy Truman followed by Cat Yronwode for the bulk of its 50 issue run.

[6] He produced a three-issue adaptation of J. R. R. Tolkien's The Hobbit for Eclipse with artist David Wenzel between 1989 and 1990, and began writing Marc Spector: Moon Knight in June 1989 for editor Potts.

[8] This led to both an ongoing monthly series[9] which Dixon wrote for 100 issues before leaving to work with CrossGen Comics, and to Dixon working on Detective Comics from #644 (May 1992)[10] to #738 (Nov. 1999) through the major Batman stories "Knightfall'"[11] and "KnightsEnd"[12] for which he helped create the key character of Bane,[13] "Contagion",[14] "Legacy",[15] "Cataclysm",[16] and "No Man's Land".

In addition to writing Detective Comics he pioneered the individual series for Robin, Nightwing (which he wrote for 70 issues, and returned to briefly with 2005's #101) and Batgirl, as well as creating the team and book Birds of Prey.

[20] While writing multiple Punisher and Batman comics and October 1994's Punisher/Batman crossover, he launched Team 7 for Jim Lee's WildStorm/Image and Prophet for Rob Liefeld's Extreme Studios.

He wrote the Ruse spin-off Archard's Agents one-shots in January and November 2003 and April 2004, the last released shortly before CrossGen's cancellation of all of its series.

In July 2004, Dixon began his return to the DC Universe with Richard Dragon, a revival of the 1970s kung-fu character, which ran for 12 issues.

He wrote Batman and the Outsiders, a project he was signed to at the last minute, after original writer Tony Bedard dropped out due to being occupied with Final Crisis-related work.

"[35] He nonetheless did occasional work for DC after this, including 2017's Bane: Conquest limited series,[36][37] and a special issue for Robin's 80th anniversary.

In 2025, Chuck Dixon will be writing several issues for Rippaverse Comics including Alphacore #2, The Great War of Seperation limited series, Zalen: What Kills, Must Die, and The Horseman #1.