Charles Wayne Osborne Jr. (November 2, 1973 – October 16, 2012) was an American professional football defensive tackle who played three seasons in the National Football League (NFL) with the St. Louis Rams and Oakland Raiders.

Osborne was also a member of the Amsterdam Admirals, Green Bay Packers, New England Patriots, and Georgia Force.

[5] He was selected by the St. Louis Rams in the seventh round, with the 222nd overall pick, of the 1996 NFL draft.

[7] He played in 15 games, starting one, for the Rams during the 1996 season, recording 11 solo tackles, one sack, and one forced fumble.

[7] Osborne played for the Amsterdam Admirals during the 1998 NFL Europe season, accumulating 20 defensive tackles, eight sacks, one forced fumble, and two pass breakups.

"[9] He is one of at least 345 NFL players to be diagnosed after death with CTE, which is caused by repeated hits to the head.