The Church of San Ferdinando is a historic church located on the Piazza Triesti e Trento, near the Royal Palace of Naples, in central Naples, Italy.

The original church at the site was dedicated by the Jesuits to Saint Francis Xavier, and was built in 1636.

The vault has a fresco with the story of Saint Francis Xavier and other Jesuits by Paolo De Matteis.

The church contains statues by Domenico Antonio Vaccaro and Giuseppe Sanmartino.

The main altarpiece is a canvas depicting San Ferdinando by Federico Maldarelli.