From 2017 to 2019, Layne starred as Shemekka Epps in the Netflix comedy-drama series, She's Gotta Have It.

[1] She made her screen debut appearing in the HBO drama film Life Support (2007), and later that year played the leading role and serviced as a producer in the independent drama film A Deeper Love.

[2] The following year, Layne appeared in a small role in the biographical drama film Cadillac Records.

[4] Since then, Layne appeared in a number of independent and made-for-television films and guest-starred on television series Workaholics and Major Crimes.

From 2017 to 2019, Layne starred as Shemekka Epps in the Netflix comedy-drama series, She's Gotta Have It.