[2] Epstein attended King Alfred School and then studied Italian at the University College, London.
[2] Epstein first began to work in archaeology when she helped a team of archaeologists excavating Tel Hazor in 1952.
After the Six Day War, in 1967, Epstein, working with Shemaryahu Gutman, was the leader of the archaeological emergency survey in the Golan area.
[1] Epstein continued to work on the Chalcolithic sites in the Golan region, which she "almost single-handedly discovered, excavated, and reported" on.
[2] Her monograph describes the unique features of the Golan site which include "house-chains" which are broad-houses linked together in long lines.
[5] Epstein's analysis of the stratigraphy of Megiddo's sacred areas was also an important part of her body of work.