Two years later, Guerrero was crowned the 2005 World Ranking Masters Champion, defeating Wendy Chai of Malaysia, 2-1, in the best-of-three-game finals.

The Colombian finished atop the women's leaderboard with 4989 24-game total and an average of 207,88 to lock up her spot for the 2006 World Ranking Masters in Kuwait.

To earn the All-Events medal (combined results of Singles, Doubles, Trios and Team), she fired a 258-game to secure a 5,330 pinfall total and an average of 222.08 over 24 games.

In the Semifinals match Guerrero posted the highest 3-game series ever in the history of the World Championships behind games of 248, 268 and 289 for an 805 total.

Guerrero made history at the World Women's Championships, she is the first bowler ever to win the All-Events and Masters event in the same year.

She captured the silver medal in All-Events, Trios, and Teams at the 2009 Pan-American Adult Championship in Puerto Rico.

The event was held in Bogota, Colombia Wednesday December 2 of 2009 in a very important ceremony with the participation of the highest athletic personalities of the country.

Clara achieved what experts believe to be a historic record by winning gold in both All Events and Masters in the 2009 Women's World Championships in Las Vegas in August.

In March 2010, Guerrero represented her country at the Juegos Suramericanos (South-American Games) held in Medellín, Colombia.

14 years after starting her international career with a runner-up finish at the QubicaAMF Bowling World Cup in Lisbon, Portugal, Guerrero lifted the trophy in Wroclaw, Poland after defeating Sin Li Jane from Malaysia in the best-of-three format, two-games-to-one.

She defeated Shannon Pluhowsky from the host country United States, two-games-to-none, to win her second consecutive World Cup title at Sam's Town Hotel, Casino & Bowling Center.

After splitting the first two games of the best-of-three final versus USA's Shannon O'Keefe, Clara was defeated 245-225 in the deciding match.

[5] On October 26, 2013, Guerrero became the third woman in history to make the TV finals for a standard PBA Tour event.

However, she lost her lone match in the May 24 televised finals to #2 seed Birgit Noreiks of Germany, taking home the $30,000 runner-up prize.