Clarence is a village in Natchitoches Parish, Louisiana, United States.

The Harrisonburg Road or the Natchez Trace ran through the area as it crossed Louisiana into Texas to connect with the El Camino Real.

As of the 2020 United States census, there were 326 people, 131 households, and 58 families residing in the village.

[6] According to the United States Census Bureau, the village has a total area of 1.6 square miles (4.1 km2), all land.

Climate is characterized by relatively high temperatures and evenly distributed precipitation throughout the year.