[2] In 1917, Seymour appeared in Pathé's Mystery of the Double Cross opposite actress Mollie King.

Seymour accepted and relocated to Los Angeles to perform as the leading lady in the Toto the Clown (played by Armando Novello) film comedy serials.

[2] Throughout 1918, she appeared in the Toto serial and also had a supporting role in the comedy short Just Rambling Along (1918), opposite Stan Laurel.

Heerman directed a screen test featuring Seymour and one of D.W. Griffith's Artcraft stock company actors Robert Harron.

[5] Griffith was pleased with the pairing and with Seymour's knack for light comedy and hired her as member of his stock company.

[6] Griffith cast Seymour with Harron, Richard Barthelmess and Carol Dempster in the drama The Girl Who Stayed at Home (1919).

A tiny girl with enormous eyes, she was as dark and vivacious as Griffith’s heroines had been blonde and wistful, a delightful girl of excellent character, whom everybody in the studio loved…” Wagenknecht laments her passing in 1920, and “what almost certainly [would] have been an important film career.”[8] In early 1920, Griffith again cast Seymour, this time in Way Down East.