Following a brawl involving her (and other judoka, who were acquitted) for violence committed at the INSEP against Anne-Fatoumata M'Bairo on April 12, 2013, she was sentenced by the Federation to a one-year suspended competition ban (three months for Priscilla Gneto, Madeleine Malonga, Fanny Posvite and Linsay Tsang Sam Moi), then in July 2014 by the courts to 70 hours of community service and a fine of 2,780 euros.

A few months later, on September 1, 2017, she was crowned world champion in the under 63 kg category in Budapest, defeating Slovenia's Tina Trstenjak, who had beaten her in the final of the Olympic Games a year earlier.

On August 28, 2019, Clarisse Agbégnénou became world champion for the fourth time at the Nippon Budokan, Tokyo's legendary martial arts and concert hall, beating Japan's Miku Tashiro by a golden score after a particularly remarkable eleven-minute bout.

She thus becomes the most successful French judoka in history, ahead of Lucie Décosse, Gévrise Émane and Brigitte Deydier, who each have three world titles, and remains unbeaten since December 2017.

On July 27, 2021, four days after leading her delegation in the opening ceremony, she took her revenge in the final against Slovenia's Tina Trstenjak, who had beaten her at the Rio Games.

After 37 seconds in the Golden score, and thanks to a sweep that gave her Waza-ari, she won the gold medal at the Tokyo 2020 32 Olympic Games.