Frank Clarke Fraser OC FRSC (29 March 1920 – 17 December 2014) was a Canadian medical geneticist.
Among his many accomplishments, Fraser pioneered work in the genetics of cleft palate and popularized the concept of multifactorial disease.
After a few years in Dublin, where his father, Frank Wise Fraser was Canadian Trade Commissioner, the family moved to Jamaica, where he received his primary and secondary school education at Munro College.
Fraser has served as president of the major North American societies in Genetics and Teratology and has won almost every award in his field.
He collected data on recurrence risks for a number of pediatric conditions, to answer the questions of the parents of affected children.