Clarklewis serves Italian-inspired Pacific Northwest cuisine in an industrial space in southeast Portland's Buckman neighborhood.

[2] The menu has included Cortez Bay scallop ceviche, Pacific halibut with pancetta, chicken and Mulino Marino polenta, and orecchiette with gold potatoes, green beans, and pesto, among other pasta dishes.

[3] The restaurant has used meat from the bison ranch Rain Shadow El Rancho in Scio, Oregon.

[12] Lane has also been credited as a co-owner of Clarklewis via Bruce Carey's restaurant group,[13] from which he departed in 2014.

[15] Clarklewis added the private dining space, called The Kindling Room, in 2010.