He held a number of offices, including Secretary of State and Superintendent of Finances, and distinguished himself in diplomacy throughout the 1630s, particularly in respect to France's entry into the Thirty Years' War.
He was a shrewd diplomat who enjoyed exceptional favour with all factions of the French court, particularly Cardinal Richelieu and Marie de Medici.
In spite of the fierce rivalry developing between Marie de Medici and Richelieu, he was able to remain on good terms with both,[3] which placed him in a highly enviable position at the French court.
[2] Richelieu employed him on many diplomatic missions, and the success of his foreign policy was due in no small degree to Bouthillier's ability and devotion.
[3] Meanwhile, at home, his tact and amiable disposition, as well as his reputation for straightforwardness, had secured for him a unique position of influence in a court torn by jealousies and intrigues.
Trusted by the king, the confidant of Richelieu, the friend of Marie de Medici, and through his son, Leon, who was appointed in 1635 chancellor to Gaston d'Orléans, able to bring his influence to bear on that prince, he was an invaluable mediator; and the personal influence thus exercised, combined with the fact that he was at the head of both the finances and the foreign policy of France, made him, next to the cardinal, the most powerful man in the kingdom.
[3] Richelieu made him executor of his will, and Louis XIII named him a member of the council of regency which he intended should govern the kingdom after his death.